منابع مشابه
Organogenesis: Cutting to the Chase
Gonad morphogenesis in Caenorhabditis elegans requires two secreted proteases. Recent studies show that alterations of the extracellular matrix component fibulin-1 rescue gonadogenesis in the absence of these proteases. This finding is a critical step toward understanding the role of extracellular matrix in organogenesis.
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We describe a new algorithm for solving linear integer programming problems. The algorithm performs a DPLL style search for a feasible assignment, while using a novel cut procedure to guide the search away from the conflicting states.
متن کاملMetabolomics cuts to the chase to chase the cuts.
type II diabetes5. However, like most proteases, a complete picture of the targets of DPP4 is lacking, which makes it difficult to anticipate metabolic function has prompted the development of a number of small-molecule inhibitors of DPP4, including sitagliptin (Januvia), which was recently approved by the US Food Proteases are enzymes that perform the basic task of cutting up other proteins an...
متن کاملCutting to the chase: taking the pulse of label-retaining cells in kidney.
ONE OF THE OLDEST ASSAYS for identifying stem cells, DNA analog pulse-chase studies date back more than 60 years (2). The concept derives from the observation that stem cells divide only rarely to preserve their proliferative potential and reduce DNA errors that occur during chromosome duplication (1). The assay consists of two parts: a pulse of DNA analog [bromodeoxyuridine (BrdU) or tritiated...
متن کاملSupplement to pursuit tracks chase
We use a support vector machine (SVM) to obtain a classifier that best discriminates ES and CS1. SVM requires a similarity matrix S as input. This matrix describes the pair-wise distance between all samples. In our case, the samples are the ES and CS1 targets xn. We compute similarity euclidean distance between two samples S(xm,xn) = ∑ f ∑i ∑ j(xm( f , i, j)− xn( f , i, j))2 where x( f , i, j) ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2004
ISSN: 0960-9822
DOI: 10.1016/j.cub.2004.10.038